Gene name:
THBS1 (TSP-1;TSP1) ;
Protein name:
Thrombospondin-1 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homotrimer; disulfide-linked (By similarity). Can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1, alpha-V/beta-3 and alpha-IIb/beta-3. Binds heparin. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS1 with CD36.
Function:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties (By similarity). May play a role in dentinogenesis and/or maintenance of dentin and dental pulp.
Subcellular Location:
N/A
Protein Attributes:
50:
MGLAWGLGVL | LLLHACGSNR | IPESGGDNSV | FDIFELTGAA | RKRSGRRLVK |
100:
GPDPSSPAFR | IEDANLIPPV | PDKKFQDLVD | AVRAEKGFLL | LASLRQMKKT |
150:
RGTLLAVERK | DHSGQVFSVI | SNGKAGTLDL | SLTVQGKQHV | VSVEEALLAT |
200:
GQWKSITLFV | QEDRAQLYID | CEKMENAELD | VPIQSIFTRD | LASIARLRIA |
250:
KGGVNDNFQG | VLQNVRFVFG | TTPEDILRNK | GCSSSTSVFV | TLDNNVVNGS |
300:
SPAIRTDYIG | HKTKDLQAIC | GISCDELSSM | VLELRGLRTI | VTTLQDSIRK |
350:
VTEENKELAN | ELRRPPLCYH | NGVQYRTGDE | WTVDSCTECR | CQNSVTICKK |
400:
VSCPIMPCSN | ATVPDGECCP | RCWPSDSADD | GWSPWSEWTS | CSVTCGNGIQ |
450:
QRGRSCDSLN | NRCEGSSVQT | RTCHIQECDK | RFKQDGGWSH | WSPWSSCSVT |
500:
CGDGVITRIR | LCNSPSPQMN | GKPCEGKARE | TKACQKDSCP | INGGWGPWSP |
550:
WDICSVTCGG | GVQKRSRLCN | NPKPQFGGKD | CVGDVTENQI | CNKQDCPIDG |
600:
CLSNPCFAGV | QCTSYPDGSW | KCGACPPGYS | GDGVECKDVD | ECKEVPDACF |
650:
NHNGEHRCEN | TDPGYNCLPC | PPRFTGSQPF | GRGVEHATAN | KQVCKPRNPC |
700:
TDGTHDCNKN | AKCNYLGHYS | DPMYRCECKP | GYAGNGIICG | EDTDLDGWPN |
750:
EDLLCVANAT | YHCRKDNCPN | LPNSGQEDYD | KDGIGDACDD | DDDNDKIPDD |
800:
RDNCPFHYNP | AQYDYDRDDV | GDRCDNCPYN | HNPDQADTDN | NGEGDACAAD |
850:
IDGDSILNER | DNCQYVYNVD | QKDTDMDGVG | DQCDNCPLEH | NPDQLDSDSD |
900:
RIGDTCDNNQ | DIDEDGHQNN | LDNCPYVPNA | NQADHDKDGK | GDACDHDDDN |
950:
DGIPDDRDNC | RLVPNPDQKD | SDGDGRGDAC | KDDFDQDKVP | DIDDICPENV |
1000:
DISETDFRRF | QMIPLDPKGT | SQNDPNWVVR | HQGKELVQTV | NCDPGLAVGY |
1050:
DEFNAVDFSG | TFFINTERDD | DYAGFVFGYQ | SSSRFYVVMW | KQVTQSYWDT |
1100:
NPTRAQGYSG | LSVKVVNSTT | GPGEHLRNAL | WHTGNTSGQV | RTLWHDPRHI |
1150:
GWKDFTAYRW | HLSHRPKTGF | IRVVMYEGKK | IMADSGPIYD | KTYAGGRLGL |
1170:
FVFSQEMVFF | SDLKYECRDS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
ELISA Kit for Bovine Thrombospondin-1
ELISA Kit for Bovine Thrombospondin-1
ELISA Kit for Bovine Thrombospondin-1
CLIA Kit for Bovine Thrombospondin-1
CLIA Kit for Bovine Thrombospondin-1
CLIA Kit for Bovine Thrombospondin-1
Polyclonal Antibody for Bovine Thrombospondin-1
Polyclonal Antibody for Bovine Thrombospondin-1
Polyclonal Antibody for Bovine Thrombospondin-1
Monoclonal Antibody for Bovine Thrombospondin-1
Monoclonal Antibody for Bovine Thrombospondin-1
Monoclonal Antibody for Bovine Thrombospondin-1
Protein for Bovine Thrombospondin-1
Protein for Bovine Thrombospondin-1
Protein for Bovine Thrombospondin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];POSSIBLE FUNCTION;TISSUE SPECIFICITY
strain :
Holstein .
tissue :
Tooth .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-18 AND 710-1170
tissue :
Aortic endothelium .